Fractional Flow Reserve
نویسنده
چکیده
Traditionally, coronary artery disease was assessed using coronary angiographic guidance. Significant lesions were determined by the coronary angiographer. However, interobserver variability showed a significant limitation of interpretation of coronary angiography. Stent deployment and apposition were also evaluated based on angiographic appearance only. Risk factors for stent thrombosis and in-stent restenosis such as incomplete stent apposition, edge dissection, and thrombus presence were often not detected. However, in the last 10 years, the field of interventional cardiology has benefitted from the use of more objective measures of the severity of coronary artery disease. Fractional flow reserve is calculated by dividing the distal coronary pressure by the proximal coronary pressure during maximal hyperemia this article will discuss the use of fractional flow reserve in determining the severity of coronary artery lesions and whether they should be revascularized.
منابع مشابه
Correlation between intracoronary ultrasound and fractional flow reserve in long coronary lesions. A three-dimensional intracoronary ultrasound study.
INTRODUCTION AND OBJECTIVES Intracoronary ultrasound estimation of the functional significance of intermediate angiographic lesions has mainly been based on measuring the minimal lumen area. These estimates take no account of lesion length and pay insufficient attention to long coronary lesions. METHODS We included 61 lesions with visual angiographic stenosis of 40% to 70% that required treat...
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Background: Invasive Fractional Flow Reserve Obstructive coronary artery disease (CAD) produces symptoms and increases the risk of adverse cardiac outcomes. However, determining whether a particular coronary stenosis is responsible for causing myocardial ischemia can be challenging, even with invasive coronary angiography (ICA). To help guide decisions in the cardiac catheterization laboratory,...
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Background Experimental studies have shown that fractional flow reserve (defined as the ratio of maximal achievable flow in a stenotic area to normal maximal achievable flow) can be calculated from coronary pressure measurements only. The objectives of this study were to validate fractional flow reserve calculation in humans and to compare this information with that derived from quantitative co...
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INTRODUCTION AND OBJECTIVES Multivessel disease is usually present in almost half of patients with acute coronary syndromes. Angiography is insufficiently accurate to decide on coronary revascularization in moderate nonculprit lesions. There is some debate about the usefulness of fractional flow reserve assessed by intracoronary pressure wire in acute coronary syndromes. We studied the results ...
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Fractional flow reserve and complex coronary intervention.
This paper aims to provide a short overview of the theoretical background for coronary pressure-derived fractional flow reserve (FFR) index and to focus on its clinical applicability in complex coronary intervention.
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